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Most people find taking it in the AM the easiest

Measure hepatic transaminases, total bilirubin, alkaline phosphatase in SYMPTOMATIC patients to evaluate hepatotoxicty ( those with jaundice, fatigue , pruritus, nausea & vomiting, abdominal pain)

Accordingly, much of the heterogeneity in the existing literature may reflect differences in endpoint level, ascertainment strategy, and control of confounding, rather than the absence of a biological effect

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